GPCRsignal: web server for analysis of the interface between G protein-coupled receptors and their effector proteins by dynamics and mutations.
P. Miszta, P. Pasznik, S. Niewieczerzał, J. Jakowiecki, S. Filipek. GPCRsignal: webserver for analysis of the interface between G-protein–coupled receptors and their effector proteins by dynamics and mutations, Nucleic Acids Res. (2021) doi:10.1093/nar/gkab434
P. Miszta, P. Pasznik, J. Jakowiecki, A. Sztyler, D. Latek, S. Filipek, GPCRM: a homology modeling web service with triple membrane-fitted quality assessment of GPCR models, Nucleic Acids Research (2018), Web Server Issue (W1), doi:10.1093/nar/gky429
D. Latek, P. Pasznik, T. Carlomagno, S. Filipek (2013) Towards improved quality of GPCR models by usage of multiple templates and profile-profile comparison.
PLOS ONE 8(2): e56742, doi:10.1371/journal.pone.0056742
ERNEST = European Research Network on Signal Transduction
The main scientific objective of the Action is to develop a common, comprehensive and holistic map of signal transduction that will advance development of pathway-specific chemical modulators. This unique and innovative goal will be realised by linking of a diverse group of researchers in the field through the networking activities funded by COST.
Our service GPCRM is completely reshaped, much faster, and user friendly. Now, it contains 3 main routes: Quick path (default), Long path, and High similarity (the fastest) for homology modeling of GPCRs. Currently, the service contains over 90 template structures. The updated version was recently published in NAR 2018, W1.