|S. Yuan, U. Ghoshdastider, B. Trzaskowski, D. Latek, A. Debinski, W.
Pulawski, R. Wu, V. Gerke, S. Filipek, The role of water in
activation mechanism of human N formyl Peptide Receptor 1 (FPR1) based
on molecular dynamics simulations, PLOS ONE (2012) 7, e47114. doi: 10.1371/journal.pone.0047114.
||Formyl Peptide Receptor 1 (FPR1)
with agonist fMLF
with antagonist tBocMLF.
The models contain water molecules within a distance < 3 Å from the complex.
Agonist fMLF located deep in binding site of FPR1.
|T.M. Stepniewski, S. Filipek, Non-peptide ligand binding to the formyl peptide receptor FPR2 - a comparison to peptide ligand binding modes, Bioorg. Med. Chem. (2015) 23, 4072-4081. doi: 10.1016/j.bmc.2015.03.062.
||Model of free FPR2 and a complex of FPR2 with agonist fMLFK.
Zones in the orthosteric binding site of FPR2.