Work group meeting and workshop
Warsaw, October 7-9, 2013

Programme in PDF.

Monday October 7

9.00-11.00 registration of participants

Session I: 11.00-14.30

(main lecture hall)
11.00-11.15 COST administrative news
11.15-11.30 Jörg Hamann (University of Amsterdam, Netherlands) Adhesion class GPCRs take the stage – Activities within the Adhesion-GPCR Consortium
11.30-11.55 Hugo Gutierrez de Teran (Uppsala University, Sweden) Molecular dynamics simulations and Free Energy Calculations can contribute to the structural and functional characterization of GPCRs
12.00-12.25 Andrea Bortolato (Heptares therapeutics, UK) Can Molecular Modelling Be the Link Among the GLISTEN WGs?
12.30-13.00 coffee break
13.00-13.25 Henry Vischer (VU University Amsterdam, Netherlands) Biased signaling by histamine receptors
13.30-13.55 Jesper M. Mathiesen (Zealand Pharma, Denmark) mRNA-display G protein-derived peptides as novel intracellular modulators of the beta2-adrenergic receptor
14.00-14.30 poster presentations, 6 x 5 min - Marian Castro, Sanja Glisic, Albert J. Kooistra, Maura Malińska, David Rodríguez, Jacek Wabik
14.30-16.00 Lunch + poster session
MC meeting (seminar room)
Session II: 16.00-19.30 (main lecture hall)
16.00-16.25 Gert Vriend (Nijmegen Centre for Molecular Life Sciences, Netherlands) A fresh look at the GPCR structures reveals novel problems/opportunities
16.30-16.55 David Gloriam (University of Copenhagen, Denmark) GPCRDB: New web tools for GPCR structures, binding site comparisons and visualisation
17.00-17.25 Masha Niv (The Hebrew University, Rehovot, Israel) GPCRs and promiscuity: the case of chemosensory receptors
17.30-18.00 coffee break
18.00-18.25 Jana Selent (Universitat Pompeu Fabra, Barcelona, Spain) Strategies to treat CNS disorders: allosteric modulation of G protein-coupled receptors
18.30-18.55 Peter Gmeiner (Pharmazeutische Chemie Erlangen, Germany) Molecular probes selectively addressing GPCRs
19.00-19.25 Xavier Leroy (Actelion) Characterization of GPCR signalling pathways: in-vitro, but not only
From 19.30 Evening program - dinner with music in pub at Pola Mokotowskie

Tuesday October 8

Workshop I: 9.00-12.30 Homology modeling of GPCRs and optimization in the membrane (Slawomir Filipek group)
9.00-10.30 part 1 - Homology modeling of GPCR structures - Vojtech Spiwok, Jens Carlsson, Daniele Castagnolo, Helena Danielson, David Gloriam (computer room)
10.30-11.00 coffee break
11.00-12.30 part 2 – Embedding and optimization in model membrane - Sanja Glisic, Zafiroula Georgoussi, V. Edda Benediktsdóttir, Hugo Gutiérrez de Terán, Ehud M. Landau (computer room)
12.30-13.30 lunch
9.00-12.30 (in parallel) WG4 short presentations (Vojtech Spiwok, Jens Carlsson, Daniele Castagnolo, Helena Danielson, David Gloriam) and discussions (main lecture hall)

Workshop II: 13.30-17.00

Ligand docking and MD simulations (Peter Kolb group)
13.30-15.00 part 1 (computer room)
15.00-15.30 coffee break
15.30-17.00 part 2 (computer room)
13.30-17.00 (in parallel) Individual Work Group meetings (seminar rooms)
From 17.00 Guided Citi Tour (Classic Warsaw with a twist - PDF)

Wednesday October 9

Workshop III: 9.00-12.30 In silico chemogenomics and virtual screening (Chris de Graaf group)
9.00-10.30 part 1 (computer room)
10.30-11.00 coffee break
11.00-12.30 part 2 (computer room)
12.30-13.30 lunch

Workshop IV: 13.30-17.00

Simulating the complex nature of membrane lipid-GPCR interaction (Jana Selent group)
13.30-15.00 part 1 - Modeling the biophysical properties of membrane lipids (computer room)
15.00-15.30 coffee break
15.30-17.00 part 2 - Simulating membrane lipid-GPCR interaction for systems generated in workshop I (computer room)
From 17.00 Individual visits to restaurant, departures.

Thursday October 10

Departure of workshop participants

It is possible to use your laptops with Linux during workshops I-IV. In this case the laptops will be used as graphics terminals and all programs will be run on servers. No prior installation of any programs on laptops is necessary.

Due to limited number of computer terminals please register as soon as possible for the Workshops. Otherwise your laptops must be used.

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